Billy blasted McCain on Twitter after the Fox News host posted a message disparaging Meryl's harsh critique of Donald Trump, calling her a "f****** moron."
Meghan fired back, saying Billy lived in a "bubble" and was part of the problem between Hollywood and the Republican Party. That only made Billy go off again ...
Billy's known to speak his mind on his game show, "Billy on the Street," where he stops people at random for pop quiz questions ... usually with a celeb in tow. We're guessing Meghan's not a fan.
She never responded after her 2nd tweet, so ... score one for Billy?
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